Keyphrases
Isocitrate Dehydrogenase 1 (IDH1)
81%
Glioma
55%
Mutant Isocitrate Dehydrogenase
32%
IDH mutation
30%
Oncometabolite
26%
Astrocytoma
25%
DNA Damage
25%
IDH-mutant Glioma
21%
Tumor
19%
Low-grade Glioma
17%
Genetically Engineered Mouse Models
14%
In Cancer
13%
2-Hydroxyglutarate (2-HG)
13%
Isocitrate Dehydrogenase Inhibitor
11%
Neuro-oncology
11%
Protein mutations
11%
Nucleotide Metabolism
11%
Epigenetic Signal
11%
Isocitrate Dehydrogenase mutation
11%
Consensus Review
11%
Patient-derived Organoids
11%
Pyrimidine Biosynthesis
11%
Adult-type Diffuse Gliomas
11%
T Cell Metabolism
11%
Glioblastoma
11%
Lanosterol Synthase Inhibitors
11%
Diagnosis Management
11%
CD8+ T Cell Infiltration
11%
Multiple Myeloma
11%
BIN3
11%
Electron Transport Chain Activity
11%
Vulnerability
11%
Computational Assessment
11%
Venetoclax
11%
Mismatch Repair Proteins
11%
Epigenetic Instability
11%
Indigo
11%
DNA Sensing
11%
Tumor Immunity
11%
KDM5
11%
Single-stranded DNA (ssDNA)
11%
PARP Inhibitor (PARPi)
10%
Metabolic Genes
10%
Diffuse Glioma
9%
Mismatch Repair
7%
Tumor Cells
7%
Cancer Therapy
7%
Nucleotide Synthesis
6%
Primary Brain Tumor
6%
Adenovirus
5%
Magnetic Resonance Imaging
5%
Histone Methylation
5%
Isocitrate Dehydrogenase 1 mutation
5%
High Prevalence
5%
Genetically Engineered Mice
5%
Organoids
5%
Oncogene
5%
Gene mutation
5%
Synthesis Pathway
5%
Epigenetic Marks
5%
Virus-like Particles
5%
Transgenic Mice
5%
Postsurgical
5%
DNA Repair
5%
Glioma Cells
5%
Leukemia
5%
Biochemistry, Genetics and Molecular Biology
Isocitrate Dehydrogenase
71%
Pyrimidine Biosynthesis
34%
DNA Damage
28%
Chromosome Instability
28%
Mouse Model
25%
Epigenetics
25%
Gene Expression Profiling
22%
Cancer Cell
18%
Metabolite
18%
DNA Mismatch Repair
17%
IDH1
16%
Enzyme
14%
Nucleotide Metabolism
14%
Genetically Engineered Mouse Strain
14%
Oxidoreductase
14%
Mouse
14%
Wild Type
14%
Ferroptosis
11%
Ubiquinone
11%
Electron Transport Chain
11%
IC50
11%
DNA Methylation
11%
Body Weight
11%
Reductase
11%
Pharmacokinetics
11%
Cell Death
11%
Oxygenation
11%
Marker Gene
11%
Lanosterol Synthase
11%
Protoporphyrin IX
11%
Preclinical Study
11%
Genetics
11%
Aggression
11%
Demethylase
11%
Lysine
11%
Tumor Immunity
11%
Myeloid
11%
Histone
11%
Lipid
9%
Metabolic Pathway
8%
Poly ADP Ribose Polymerase
8%
Heme Synthesis
7%
Mitochondrial Respiration
7%
Clinical Trial
7%
Methylation
7%
Dihydroorotate Dehydrogenase
5%
Estrogen Receptor
5%
Murine
5%
Disease Modeling
5%
DNA Repair
5%
Histone Demethylation
5%
Uridine Monophosphate
5%
Glutaminase
5%
Animal Model
5%
Syngenic
5%
Gene Mutation
5%
Uridine
5%
Tumor Progression
5%
Metabolomics
5%
Cell Transformation
5%
Progression Free Survival
5%
Transcriptomics
5%
Cell Metabolism
5%
Overall Survival
5%
Medicine and Dentistry
Ganglioglioma
100%
Malignant Neoplasm
77%
Neoplasm
39%
Isocitrate Dehydrogenase
39%
Organoid
34%
DNA Damage
22%
2 Hydroxyglutaric Acid
22%
Chromosomal Instability
15%
Xenograft
14%
Brain Tumor
13%
Cell Metabolism
12%
Breast Cancer
12%
T Cell
11%
Neuro-Oncology
11%
Cell Function
11%
Poly ADP Ribose Polymerase
11%
Aminolevulinic Acid
11%
Triple Negative Breast Cancer
11%
DNA Repair
11%
Oncology
11%
Lanosterol Synthase
11%
Nucleotide Metabolism
11%
Gene Mutation
11%
Therapeutic Modality
11%
Histone Demethylation
11%
Cytotoxic T-Cell
11%
Cancer Therapy
11%
Oligoastrocytoma
11%
Aggression
11%
Lysine
11%
Histone
11%
Isocitrate Dehydrogenase Inhibitor
9%
Acute Myeloid Leukemia
8%
Tumor Cell
7%
Pyrimidine Synthesis
5%
Breast Tumor
5%
Gene Expression Profiling
5%
Cell Transformation
5%
Molecular Pathology
5%
Cell Line
5%
Carcinogenesis
5%
Solid Malignant Neoplasm
5%
Combination Therapy
5%