Bioinformatics

Sequencing data processing and analysis: The Resource has developed processing and analysis pipelines for high-throughput next-generation sequence (NGS) data, such as RNA-seq, ChIP-seq, miRNA-seq and CLIP-seq. The input to the NGS pipeline is either raw reads from the sequencing machines or mapped reads from alignment software.
Microarray data processing and analysis: Bioinformatics personnel will help investigators on microarray data processing and analysis, including background correction, normalization, summarization, quality control, detecting differentially expressed genes, and correlation of gene expression with phenotypes or clinical variables.
Bioinformatics: The Resource is available to help investigators with bioinformatics analysis, such as pathway and gene function enrichment analysis and gene network analysis.
Database, software and web interface development: Services include design and implementation of interactive web applications as well as the underlying database back-ends. Support is available for investigators with problems concerning data acquisition, management, and analysis.
High-performance computing systems access: Bioinformatics personnel can configure, maintain, and administer high-performance computing resources for Cancer Center investigators. The Resource has a suite of servers and computer clusters available for researchers to analyze and store data.
Grant-writing assistance: Support is available for proposals seeking to integrate modern computational techniques in research activities; practical training; and data analysis.
‘Walk-in’ clinics and other training: Free consultations for Cancer Center members are available weekly on data analysis and accessing computation servers. Also, the Resource provides hands-on practical workshops on how to access the high-performance computational cluster, Unix/Linux environment, and basic programming skills.