Benign prostatic hyperplasia (BPH) is a common cause of urinary outflow obstruction in aging men leading to lower urinary tract symptoms (LUTS). α1-Adrenoceptors (α1ARs) antagonists (blockers) have become a mainstay of LUTS treatment because they relax prostate smooth muscle and decrease urethral resistance, as well as relieving bladder LUTS symptoms. A review of key recent clinical trials suggests new insights into the role of specific α1AR subtypes in the treatment of LUTS.
|Original language||English (US)|
|Number of pages||7|
|Journal||International Journal of Urology|
|State||Published - Mar 2008|
- Alpha blockers
- Benign prostatic hyperplasia
ASJC Scopus subject areas