What sugar does to your pores

Jennifer J. Kohler

doi:10.1083/jcb.202105163

What sugar does to your pores

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

FG-repeat nucleoporins at the center of the nuclear pore complex (NPC) are highly modified with O-GlcNAc. In this issue, Yoo and Mitchison (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010141) use optogenetic probes to show that O-GlcNAc enhances permeability of the NPC, accelerating transport in both directions.

Original language	English (US)
Article number	e202105163
Journal	Journal of Cell Biology
Volume	220
Issue number	7
DOIs	https://doi.org/10.1083/jcb.202105163
State	Published - Jul 5 2021

ASJC Scopus subject areas

Cell Biology

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10.1083/jcb.202105163

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title = "What sugar does to your pores",

abstract = "FG-repeat nucleoporins at the center of the nuclear pore complex (NPC) are highly modified with O-GlcNAc. In this issue, Yoo and Mitchison (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010141) use optogenetic probes to show that O-GlcNAc enhances permeability of the NPC, accelerating transport in both directions.",

author = "Kohler, {Jennifer J.}",

note = "Funding Information: Research on O-GlcNAc in the author{\textquoteright}s laboratory is funded by the NIH Common Fund (U01CA242115).",

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N2 - FG-repeat nucleoporins at the center of the nuclear pore complex (NPC) are highly modified with O-GlcNAc. In this issue, Yoo and Mitchison (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010141) use optogenetic probes to show that O-GlcNAc enhances permeability of the NPC, accelerating transport in both directions.

AB - FG-repeat nucleoporins at the center of the nuclear pore complex (NPC) are highly modified with O-GlcNAc. In this issue, Yoo and Mitchison (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010141) use optogenetic probes to show that O-GlcNAc enhances permeability of the NPC, accelerating transport in both directions.

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What sugar does to your pores

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