What Is Evidence-Based Medicine? Critical Thinking Skills Symposium

Kelly H. Zou, Julia R. Fielding, Silvia Ondategui-Parra

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Rationale and Objectives. In this review article, we present the definition and useful concepts of evidence-based medicine (EBM). The principles of EBM are provided and major steps of practicing EBM are described. Materials and Methods. We emphasize the importance of the Cochrane Collaboration (see http://www.cochrane.org), which initiated the research and practice in this area. Because it can be difficult to systematically access and review individual research studies, it is often useful to focus on a critical overview of clinical trials by conducting a meta-analysis. Results. Useful literature and resources related to meta-analysis are provided. Conclusion. Statistical methods for evaluating radiologic diagnostic performances derived from meta-analysis are summarized, with a special focus on summary outcomes measures.

Original languageEnglish (US)
Pages (from-to)127-133
Number of pages7
JournalAcademic radiology
Issue number2
StatePublished - Feb 2004


  • Evidence-based medicine
  • Evidence-based radiology
  • Meta-analysis
  • Receiver operating characteristic curve
  • Sensitivity
  • Specificity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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