Volumetric cat measures and neuropsychological performance in alzheimer's disease

E. D. Bigler, D. Hubler, E. Turkheimer, C. M. Cullum, S. Paver, R. Yeo

Research output: Contribution to journalArticlepeer-review


The following measures were computer generated from CAT scans of 31 patients with degenerative disorder (Alzheimer's type): Brain surface area (BSA), Brain volume (BV), Ventricular surface area (VSA), Ventricular volume (VV), and an Atrophy Index determined by the BSA/√BV. Left and right hemisphere measurements were also determined for BSA, BV, VSA and VV. All patients received a standard neuropsychological battery of tests. Correlational analyses were then undertaken between the various CAT scan measures and neuropsychological performance. Results indicate that VV and the Atrophy Index measures are the most sensitive for the detection of degenerative morphological brain changes in relationship to neuropsychological impairment in the degenerative patient.

Original languageEnglish (US)
Pages (from-to)291-294
Number of pages4
JournalInternational Journal of Neuroscience
Issue number3-4
StatePublished - 1984

ASJC Scopus subject areas

  • Neuroscience(all)


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