Vitamine C et risque lithiasique

Translated title of the contribution: Vitamin C and stone risk. Review of the literature

Olivier Traxer, Margaret S Pearle, Bernard Gattegno, Philippe Thibault

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


The popularity of vitamin C can be attributed to Linus Pauling who, in the 1970s, recommended the use of vitamin C for the prevention of influenza. Vitamin C has subsequently been used extensively in a wide range of diseases. Ascorbic acid (vitamin C) has been incriminated as a possible risk factor for calcium oxalate stones due to its enzymatic conversion into oxalate. However, this lithogenic role has never been clearly established. Studies evaluating the effect of ascorbic acid on lithogenesis have reported contradictory results. Ascorbic acid has also been extensively used as an urine acidifier for the treatment of chronic or recurrent urinary tract infection. Once again, the data of the literature are contradictory. The purpose of this article was to review the effects of ascorbic acid on lithogenesis and urinary pH based on a review of the literature.

Translated title of the contributionVitamin C and stone risk. Review of the literature
Original languageFrench
Pages (from-to)1290-1294
Number of pages5
JournalProgres en Urologie
Issue number6
StatePublished - Dec 1 2003


  • Ascorbic acid
  • Oxalate
  • Renal calculi
  • Urolithiasis
  • Vitamin C

ASJC Scopus subject areas

  • Urology


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