Abstract
Background.: Verrucous carcinoma is a rare condition. A defined disease of the oral cavity, larynx, esophagus, skin, vulva, vagina and cervix. But a verrucous carcinoma arising from the endometrium without evidence of cervical malignancy or endometrial adenocarcinoma is extremely rare. Case.: A 67-year-old G2P2 menopausal patient that was referred for consultation 1 year after presenting with vaginal bleeding to her gynecologist who subsequently underwent several endometrial biopsies where the pathological findings were repetitively similar: papillary squamous proliferation, cytologically bland with low mitotic activity but extensive proliferation. A hysterectomy with bilateral salpingo-oophorectomy was performed. The final histologic examination revealed a squamous cell carcinoma of endometrium, verrucous and well differentiated, and there was no cervical invasion identified. Conclusion.: This is a rare form of endometrial cancer with apparent favorable prognosis that must be considered when squamous cells are identified on endometrial samplings.
Original language | English (US) |
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Pages (from-to) | 375-377 |
Number of pages | 3 |
Journal | Gynecologic oncology |
Volume | 102 |
Issue number | 2 |
DOIs | |
State | Published - Aug 2006 |
Keywords
- Endometrium
- Hyperkeratosis
- Squamous cell carcinoma
- Squamous papilloma
- Verrucous carcinoma
ASJC Scopus subject areas
- Oncology
- Obstetrics and Gynecology