TY - JOUR
T1 - Ventricle size, cortical atrophy and the relationship with neuropsychological status in closed head injury
T2 - a quantitative analysis.
AU - Cullum, C. M.
AU - Bigler, E. D.
PY - 1986/8
Y1 - 1986/8
N2 - Forty-eight patients with a history of moderate to severe closed-head injury (CHI) were examined with neuropsychological measures and computerized tomography (CT). CT scans were assessed with computerized techniques to determine estimated ventricular volumes (VV) and the degree of cortical atrophy (ATVOL) in each patient. VV's then were used to determine volumetric ventricle-brain ratios (VBR) to correct for head size. The WAIS, Wechsler Memory Scale (WMS) and Halstead-Reitan Neuropsychological Test Battery (HRNTB) were administered to all patients. Correlational analyses were undertaken between VBR and ATVOL measures. PIQ but not VIQ was negatively correlated with VBR and ATVOL, particularly in terms of right-hemisphere measures. WMS Memory Quotient (MQ) also was negatively correlated with VBR and ATVOL with no lateralization. Several HRNTB measures similarly were correlated with ventricular and atrophy estimates. Correlational results also were analyzed in terms of the influence of higher and lower VBR and ATVOL, and the prior presence of hematoma. Results are discussed in terms of the latent effects of cerebral damage secondary to CHI on neuropsychological functioning.
AB - Forty-eight patients with a history of moderate to severe closed-head injury (CHI) were examined with neuropsychological measures and computerized tomography (CT). CT scans were assessed with computerized techniques to determine estimated ventricular volumes (VV) and the degree of cortical atrophy (ATVOL) in each patient. VV's then were used to determine volumetric ventricle-brain ratios (VBR) to correct for head size. The WAIS, Wechsler Memory Scale (WMS) and Halstead-Reitan Neuropsychological Test Battery (HRNTB) were administered to all patients. Correlational analyses were undertaken between VBR and ATVOL measures. PIQ but not VIQ was negatively correlated with VBR and ATVOL, particularly in terms of right-hemisphere measures. WMS Memory Quotient (MQ) also was negatively correlated with VBR and ATVOL with no lateralization. Several HRNTB measures similarly were correlated with ventricular and atrophy estimates. Correlational results also were analyzed in terms of the influence of higher and lower VBR and ATVOL, and the prior presence of hematoma. Results are discussed in terms of the latent effects of cerebral damage secondary to CHI on neuropsychological functioning.
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U2 - 10.1080/01688638608401333
DO - 10.1080/01688638608401333
M3 - Article
C2 - 3745416
SN - 1380-3395
VL - 8
SP - 437
EP - 452
JO - Journal of clinical and experimental neuropsychology : official journal of the International Neuropsychological Society
JF - Journal of clinical and experimental neuropsychology : official journal of the International Neuropsychological Society
IS - 4
ER -