Vasoactive intestinal polypeptide: Abundant immunoreactivity in neural cell lines and normal nervous tissue

Sami I. Said, Roger N. Rosenberg

Research output: Contribution to journalArticlepeer-review

392 Scopus citations

Abstract

Vasoactive intestinal polypeptide immunoreactivity is present in high concentrations in clonal lines of neuronal and glial origin. The central nervous system and sympathetic ganglia are also rich in the peptide. The findings suggest that this peptide, hitherto thought limited to the gastrointestinal tract, is widely distributed in neural tissue and may have broad physiological significance.

Original languageEnglish (US)
Pages (from-to)907-908
Number of pages2
JournalScience
Volume192
Issue number4242
DOIs
StatePublished - Jan 1 1976

ASJC Scopus subject areas

  • General

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