Vascular patterning: Coordinated signals keep blood vessels on track

Stryder M. Meadows; Ondine Cleaver

doi:10.1016/j.gde.2015.02.002

Vascular patterning: Coordinated signals keep blood vessels on track

Stryder M. Meadows, Ondine Cleaver

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

The vascular system is a complex, largely stereotyped network of interconnecting and branching vessels. How thousands of vessels form at precise locations is a key question regarding vascular morphogenesis. In order to achieve this defined architecture, the embryo integrates a multitude of attractive and repulsive cues to guide and shape the developing vasculature. This review summarizes recent studies investigating the interactions between endothelial cells and signals from surrounding tissues that pattern the initial blood vessel network.

Original language	English (US)
Pages (from-to)	86-91
Number of pages	6
Journal	Current Opinion in Genetics and Development
Volume	32
DOIs	https://doi.org/10.1016/j.gde.2015.02.002
State	Published - Jun 1 2015

ASJC Scopus subject areas

Genetics
Developmental Biology

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10.1016/j.gde.2015.02.002

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title = "Vascular patterning: Coordinated signals keep blood vessels on track",

abstract = "The vascular system is a complex, largely stereotyped network of interconnecting and branching vessels. How thousands of vessels form at precise locations is a key question regarding vascular morphogenesis. In order to achieve this defined architecture, the embryo integrates a multitude of attractive and repulsive cues to guide and shape the developing vasculature. This review summarizes recent studies investigating the interactions between endothelial cells and signals from surrounding tissues that pattern the initial blood vessel network.",

author = "Meadows, {Stryder M.} and Ondine Cleaver",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Ltd.",

year = "2015",

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AU - Cleaver, Ondine

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AB - The vascular system is a complex, largely stereotyped network of interconnecting and branching vessels. How thousands of vessels form at precise locations is a key question regarding vascular morphogenesis. In order to achieve this defined architecture, the embryo integrates a multitude of attractive and repulsive cues to guide and shape the developing vasculature. This review summarizes recent studies investigating the interactions between endothelial cells and signals from surrounding tissues that pattern the initial blood vessel network.

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Vascular patterning: Coordinated signals keep blood vessels on track

Abstract

ASJC Scopus subject areas

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