Vascular complications from anterior spine surgery in three patients with ehlers-danlos syndrome

Justin S. Yang, Paul D. Sponseller, Muharrem Yazici, Charles E. Johnston

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


STUDY DESIGN.: A case report of vascular complications arising from anterior spine surgery in 3 patients with Ehlers-Danlos syndrome (EDS). OBJECTIVE.: The aim of the article is to describe complications of anterior spine surgery in 3 patients with EDS. SUMMARY OF BACKGROUND DATA.: Scoliosis can be a skeletal manifestation of EDS. Anterior approaches to the spine are sometimes used during scoliosis surgery to gain more correction than otherwise possible. A literature search revealed no published articles focusing on major vascular bleeding during anterior spine surgery in EDS patients as the specific topic. METHODS.: Review of records and radiographs. RESULTS.: Three patients with EDS and severe scoliosis underwent an anterior and posterior release followed by posterior fusion. Major bleeding was encountered during anterior surgery in all 3 patients. Sources of bleeding included a torn external iliac artery, avulsed segmental arteries, and the abdominal aorta. Blood loss ranged from 600 mL to 6 L. All vessels were repaired with sutures and synthetic grafts. In all 3 patients, posterior fusion was met with no complications and their curves were stable at follow-up. CONCLUSION.: These complications may be explained by the fragility of blood vessels secondary to the collagen defect in EDS. Though methods exist to decrease these complications, they may not be enough to prevent catastrophic bleeding. For EDS patients, risk of vascular complications during anterior surgery of the spine is high and surgeons should be aware of this when developing a surgical plan.

Original languageEnglish (US)
Pages (from-to)E153-E157
Issue number4
StatePublished - Feb 15 2009


  • Anterior spine surgery
  • Bleeding
  • Ehlers-Danlos
  • Scoliosis
  • Vascular complications

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Clinical Neurology


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