Vaccination as a triggering event for autoimmune hepatitis

Ponni Perumalswami, Lan Peng, Joseph A. Odin

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


The pathogenesis of autoimmune hepatitis entails complex interactions between triggering factors, autoantigens, genetic predisposition, and immunoregulatory networks. Implicated triggering factors are numerous and include toxins, medications, and infectious agents. In this article, we present a unique case of a 31-year-old woman with severe autoimmune hepatitis apparently abruptly triggered by vaccination. All evidence suggests this was an idiosyncratic response to either hepatitis A or yellow fever vaccination.

Original languageEnglish (US)
Pages (from-to)331-334
Number of pages4
JournalSeminars in liver disease
Issue number3
StatePublished - Aug 1 2009


  • Autoimmune hepatitis
  • Hepatitis A
  • Vaccination
  • Yellow fever

ASJC Scopus subject areas

  • Hepatology


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