Uveitis and Posterior Ophthalmic Manifestations Following the SARS-CoV-2 (COVID-19) Vaccine

Kishan G. Patel, Taylor Hilton, Rene Y. Choi, Ashkan M. Abbey

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: To present four cases of posterior ophthalmic manifestations associated with a temporal relationship to SARS-CoV-2 vaccination. Methods: Retrospective case series with a review of clinical findings. Results: Four patients presented with various posterior ophthalmic findings including uveitis, maculopathy, and optic neuropathy. Each of their clinical courses varied in terms of ophthalmic imaging and exam findings. Conclusion: The coronavirus disease 2019 (COVID-19) pandemic has ushered in a new wave of challenges to healthcare, epidemiological endeavors, and widespread vaccination efforts. Novel vaccines have been developed for the SARS-CoV-2 virus, including both mRNA and viral vector-based platforms. The ocular manifestations and side effects related to the SARS-CoV-2 vaccine is not well established or understood. There may be an association between vaccination and posterior ophthalmic manifestations.

Original languageEnglish (US)
Pages (from-to)1142-1148
Number of pages7
JournalOcular Immunology and Inflammation
Issue number5
StatePublished - 2022
Externally publishedYes


  • Coronavirus
  • COVID-19
  • inflammation
  • maculopathy
  • mRNA
  • optic neuropathy
  • pandemic
  • uveitis
  • vaccination
  • viral

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology


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