Abstract
Background: The efficacy and safety of UVA1 (340-400nm) phototherapy were established by studies from European countries. Purpose: Evaluate experience with UVA1 phototherapy for patients with cutaneous diseases in the United States. Methods: A retrospective analysis of 92 cases of UVA1-treated cutaneous conditions from four medical centers in the United States was performed. Results: Two-third of the patients showed a fair to good response (26-100% improvement) and one-third of the patients showed a poor response (0-25% improvement). Diseases with a moderate to good response (51-100% improvement) included scleredema adultorum, hand or foot dermatitis, atopic dermatitis, morphea (medium or medium- to high-dose UVA1), systemic sclerosis, and urticaria pigmentosa. Besides tanning, other adverse effects were found in 15% of patients, which include pruritus, erythema, tenderness, and burning sensation. Patients with skin types I-III responded better that those with a darker skin type. Conclusion: UVA1 phototherapy is a useful and well-tolerated treatment option for a variety of skin conditions.
Original language | English (US) |
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Pages (from-to) | 247-253 |
Number of pages | 7 |
Journal | Photodermatology Photoimmunology and Photomedicine |
Volume | 22 |
Issue number | 5 |
DOIs | |
State | Published - Oct 2006 |
Keywords
- Ohototherapy
- UVA1
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Radiology Nuclear Medicine and imaging
- Dermatology