Urodynamics findings in transverse myelitis patients with lower urinary tract symptoms: Results from a tertiary referral urodynamic center

Louise A. Gliga, Rebecca S. Lavelle, Alana L. Christie, Burhan Coskun, Benjamin M. Greenberg, Maude E. Carmel, Gary E. Lemack

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Aims: To characterize urodynamic findings in patients referred with transverse myelitis (TM) and lower urinary tract symptoms (LUTS), as well as to identify any characteristics predictive of urodynamics findings. Methods: This is a retrospective review of an IRB-approved neurogenic bladder database of patients followed by a single surgeon between 2001 and 2013. Patient characteristics, questionnaire data, radiologic studies, and urodynamic parameters were analyzed. Results: Of the 836 patients in the neurogenic bladder database, 28 patients (17 females, 11 males) were referred with a principle diagnosis of TM (3%). Twenty-one of twenty-eight patients (75%) underwent urodynamics testing. Bladder management at initial urologic evaluation was CIC or urethral catheter for 16/28 patients (57.1%). Median MCC was 303ml (85-840ml), detrusor overactivity (DO) was present in 16/21 (76%), detrusor sphincter dyssynergia (DSD) in 10/21 (48%), and decreased compliance in 7/21 (33%). For those voiding, mean Qmax was 12±10ml/sec and pdet at Qmax was 41±17cmH2O. Longitudinally extensive TM (LETM) was the only patient characteristic associated with DO (P=0.0276). No other patient characteristics were associated with urodynamics parameters. Conclusions: Significant urodynamic testing abnormalities are noted in the majority of TM patients undergoing urodynamics, with 95% having DO, DSD, altered compliance, or detrusor underactivity. Other than the association between LETM and DO, there were no patient characteristics predictive of urodynamics findings. Based on the severity of urodynamics findings in our series, patients with TM and LUTS should have thorough baseline urological evaluations including urodynamics and be offered ongoing surveillance.

Original languageEnglish (US)
JournalNeurourology and Urodynamics
StateAccepted/In press - 2015


  • Neurogenic bladder conditions
  • Transverse myelitis
  • Urodynamics

ASJC Scopus subject areas

  • Clinical Neurology
  • Urology


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