Urine screening for chlamydia trachomatis during pregnancy

Scott W. Roberts; Jeanne S. Sheffield; Don D. McIntire; James M. Alexander

doi:10.1097/AOG.0b013e3182107d47

Urine screening for chlamydia trachomatis during pregnancy

Scott W. Roberts, Jeanne S. Sheffield, Don D. McIntire, James M. Alexander

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Objective: To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution. Methods: A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay. Results: A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]). Conclusion: Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.

Original language	English (US)
Pages (from-to)	883-885
Number of pages	3
Journal	Obstetrics and gynecology
Volume	117
Issue number	4
DOIs	https://doi.org/10.1097/AOG.0b013e3182107d47
State	Published - Apr 1 2011

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1097/AOG.0b013e3182107d47

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title = "Urine screening for chlamydia trachomatis during pregnancy",

abstract = "Objective: To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution. Methods: A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay. Results: A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]). Conclusion: Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.",

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T1 - Urine screening for chlamydia trachomatis during pregnancy

AU - Roberts, Scott W.

AU - Sheffield, Jeanne S.

AU - McIntire, Don D.

AU - Alexander, James M.

PY - 2011/4/1

Y1 - 2011/4/1

N2 - Objective: To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution. Methods: A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay. Results: A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]). Conclusion: Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.

AB - Objective: To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution. Methods: A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay. Results: A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]). Conclusion: Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.

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Urine screening for chlamydia trachomatis during pregnancy

Abstract

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