Updates in management of ampullary carcinomas

Preethi K. John, Andromachi S. Kougioumtzopoulou, Konstantinos N. Syrigos, Muhammad Wasif Saif

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations


Ampullary carcinomas are rare malignancies representing less than 1% of all gastrointestinal cancers. Given the low incidence rate, there is scarcity of data regarding the survival benefit of the treatment options available. In the 2014 ASCO Gastrointestinal Cancers Symposium there were two abstracts that discussed the role of pancreaticoduodenectomy and adjuvant radiation therapy in ampullary carcinoma. The first study (Abstract #366) demonstrated a decline in morbidity and mortality over time for pancreaticoduodenectomy making it a reasonable option for successful treatment of ampullary carcinoma. The second study (Abstract #282) showed that adjuvant radiation therapy in patients with T2 tumors had improved median survival times compared to patients that did not receive radiation therapy.

Original languageEnglish (US)
Pages (from-to)140-143
Number of pages4
JournalJournal of the Pancreas
Issue number2
StatePublished - Jan 1 2014
Externally publishedYes
Event2014 ASCO Gastrointestinal Cancers Symposium - San Francisco, CA, United States
Duration: Jan 16 2014Jan 18 2014


  • Ampulla of Vater
  • Neoplasms
  • Pancreaticoduodenectomy
  • Radiotherapy

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology


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