Unique causes of esophageal inflammation: A histopathologic perspective

Purva Gopal, Joanna A. Gibson, Mikhail Lisvosky, Ilke Nalbantoglu

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Gastroenterologists frequently perform endoscopic esophageal mucosal biopsies for pathologic diagnosis in patients experiencing symptoms of esophagitis. The more common causes of esophagitis diagnosed on esophageal mucosal biopsy include reflux esophagitis, eosinophilic esophagitis, and infectious esophagitis caused by Candida albicans, herpes simplex virus, and/or cytomegalovirus. However, there are several causes of esophagitis seen less frequently by pathologists that are very important to recognize. We discuss unique types of esophageal inflammation, including acute bacterial esophagitis, esophageal manifestations of dermatologic diseases, medication-induced esophageal injury, and sloughing esophagitis; and we review their clinical and histopathologic features.

Original languageEnglish (US)
JournalAnnals of the New York Academy of Sciences
StateAccepted/In press - Jan 1 2018


  • Acute bacterial esophagitis
  • Lichen planus
  • Pemphigus vulgaris
  • Pill esophagitis
  • Sloughing esophagitis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science


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