Unilateral renal agenesis

Jennifer S. Hernandez, Jodi S. Dashe

Research output: Chapter in Book/Report/Conference proceedingChapter


Unilateral renal agenesis has a birth prevalence of approximately 1:1000 to 1:2000, but it is often undetected prenatally. Sonographically, one kidney cannot be visualized in either the renal fossa or the pelvis, and the adrenal flattens and fills the renal fossa-the “lying-down” adrenal sign. Color Doppler imaging of the descending aorta reveals just one renal artery. The solitary kidney often develops compensatory hypertrophy. Unilateral renal agenesis is associated with other anomalies, particularly genitourinary abnormalities, and it is a component of several genetic syndromes. Therefore, targeted sonography is indicated, and amniocentesis may be offered. Affected individuals are usually asymptomatic; however, they are at increased risk to develop hypertension and renal insufficiency.

Original languageEnglish (US)
Title of host publicationObstetric Imaging
Subtitle of host publicationFetal Diagnosis and Care, 2nd Edition
ISBN (Electronic)9780323445481
StatePublished - Jan 1 2017


  • Lying-down adrenal sign
  • Renal fossa
  • Solitary kidney

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Unilateral renal agenesis'. Together they form a unique fingerprint.

Cite this