Ubiquitin Tunes Hedgehog in Matters of the Heart

Sandii Constable; Saikat Mukhopadhyay

doi:10.1016/j.devcel.2020.10.017

Ubiquitin Tunes Hedgehog in Matters of the Heart

Sandii Constable, Saikat Mukhopadhyay

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

Oligogenic inheritance makes the etiology of developmental diseases challenging to determine. In this issue of Developmental Cell, Kong et al., 2020 identify members of a membrane-tethered ubiquitin complex that attenuates Hedgehog signaling strength and genetically interact to regulate digit number, body patterning, and cardiac development.

Original language	English (US)
Pages (from-to)	385-386
Number of pages	2
Journal	Developmental cell
Volume	55
Issue number	4
DOIs	https://doi.org/10.1016/j.devcel.2020.10.017
State	Published - Nov 23 2020

ASJC Scopus subject areas

Molecular Biology
Biochemistry, Genetics and Molecular Biology(all)
Developmental Biology
Cell Biology

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10.1016/j.devcel.2020.10.017

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title = "Ubiquitin Tunes Hedgehog in Matters of the Heart",

abstract = "Oligogenic inheritance makes the etiology of developmental diseases challenging to determine. In this issue of Developmental Cell, Kong et al., 2020 identify members of a membrane-tethered ubiquitin complex that attenuates Hedgehog signaling strength and genetically interact to regulate digit number, body patterning, and cardiac development.",

author = "Sandii Constable and Saikat Mukhopadhyay",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

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AU - Mukhopadhyay, Saikat

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AB - Oligogenic inheritance makes the etiology of developmental diseases challenging to determine. In this issue of Developmental Cell, Kong et al., 2020 identify members of a membrane-tethered ubiquitin complex that attenuates Hedgehog signaling strength and genetically interact to regulate digit number, body patterning, and cardiac development.

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Ubiquitin Tunes Hedgehog in Matters of the Heart

Abstract

ASJC Scopus subject areas

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