TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION

Eric J. Weinlander, Angeline L. Wang, Pimkwan Jaru-Ampornpan, Michael M. Altaweel, T. Michael Nork

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.

Original languageEnglish (US)
Pages (from-to)241-243
Number of pages3
JournalRetinal Cases and Brief Reports
Volume13
Issue number3
DOIs
StatePublished - Jun 1 2019
Externally publishedYes

Keywords

  • acute retinal necrosis
  • prior shingles vaccination
  • varicella zoster virus

ASJC Scopus subject areas

  • Ophthalmology

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