T2-weighted 3D fast spin echo imaging with water-fat separation in a single acquisition

Ananth J. Madhuranthakam, Huanzhou Yu, Ann Shimakawa, Reed F. Busse, Martin P. Smith, Scott B. Reeder, Neil M. Rofsky, Jean H. Brittain, Charles A. McKenzie

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Purpose: To develop a robust 3D fast spin echo (FSE) T2-weighted imaging method with uniform water and fat separation in a single acquisition, amenable to high-quality multiplanar reformations. Materials and Methods: The Iterative Decomposition of water and fat with Echo Asymmetry and Least squares estimation (IDEAL) method was integrated with modulated refocusing flip angle 3D-FSE. Echoes required for IDEAL processing were acquired by shifting the readout gradient with respect to the Carr-Purcell-Meiboom-Gill echo. To reduce the scan time, an alternative data acquisition using two gradient echoes per repetition was implemented. Using the latter approach, a total of four gradient echoes were acquired in two repetitions and used in the modified IDEAL reconstruction. Results: 3D-FSE T2-weighted images with uniform water-fat separation were successfully acquired in various anatomies including breast, abdomen, knee, and ankle in clinically feasible scan times, ranging from 5:30-8:30 minutes. Using water-only and fat-only images, in-phase and out-of-phase images were reconstructed. Conclusion: 3D-FSE-IDEAL provides volumetric T2-weighted images with uniform water and fat separation in a single acquisition. High-resolution images with multiple contrasts can be reformatted to any orientation from a single acquisition. This could potentially replace 2D-FSE acquisitions with and without fat suppression and in multiple planes, thus improving overall imaging efficiency.

Original languageEnglish (US)
Pages (from-to)745-751
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Issue number3
StatePublished - Sep 2010


  • 3D FSE
  • 3D T2-weighted imaging
  • Fat suppression
  • Water-fat separation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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