Tridimensional personality questionnaire and serotonin in bulimia nervosa

David A. Waller, Christina M. Gullion, Frederick Petty, Bettie W. Hardy, Mary V. Murdock, A. John Rush

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


To determine the relationship between Tridimensional Personality Questionnaire (TPQ) scales and bulimia nervosa, TPQ scores of 27 bulimic women, age range 21-59, were compared with values for an age-matched sample of 128 normal control women drawn from the national norming sample by Przybeck. Scores for Novelty Seeking and Harm Avoidance were significantly higher, while scores for Reward Dependence were significantly lower for the bulimic women. A stepwise regression model of severity of purging on TPQ selected Novelty Seeking and a composite depression score, with Novelty Seeking being the stronger of the two predictors. Whole blood serotonin levels did not relate to TPQ scores or to purging frequency.

Original languageEnglish (US)
Pages (from-to)9-15
Number of pages7
JournalPsychiatry research
Issue number1
StatePublished - Jul 1993


  • Eating disorders
  • depression
  • fluoxetine
  • novelty seeking

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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