Treatment of the chronic total occlusion: A call to action for the interventional community

Mauro Carlino; Caroline J. Magri; Barry F. Uretsky; Emmanouil S. Brilakis; Simon Walsh; James C. Spratt; Colm Hanratty; J. Aaron Grantham; Stéphane Rinfret; Craig A. Thompson; William L. Lombardi; Alfredo R. Galassi; George Sianos; Azeem Latib; Roberto Garbo; Dimitri Karmpaliotis; David E. Kandzari; Antonio Colombo

doi:10.1002/ccd.25736

Treatment of the chronic total occlusion: A call to action for the interventional community

Mauro Carlino, Caroline J. Magri, Barry F. Uretsky, Emmanouil S. Brilakis, Simon Walsh, James C. Spratt, Colm Hanratty, J. Aaron Grantham, Stéphane Rinfret, Craig A. Thompson, William L. Lombardi, Alfredo R. Galassi, George Sianos, Azeem Latib, Roberto Garbo, Dimitri Karmpaliotis, David E. Kandzari, Antonio Colombo

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

There is substantial evidence that recanalization of a chronic total occlusion is beneficial; nonetheless, it is generally underutilized in clinical practice. We consider the Aesop's fable of the "Fox and the Grapes" as analogous to the current situation in interventional cardiology. The technical challenges in achieving CTO recanalization has led interventionalists, clinical cardiologists, and sometimes even patients to believe that CTO recanalization is not effective, and, therefore, not needed. This perspective reviews available data regarding efficacy and safety of CTO percutaneous coronary intervention (PCI) in the current drug-eluting stent era, discusses areas where more studies are required, and encourages the interventional community to utilize CTO PCI where appropriate based on current evidence.

Original language	English (US)
Pages (from-to)	771-778
Number of pages	8
Journal	Catheterization and Cardiovascular Interventions
Volume	85
Issue number	5
DOIs	https://doi.org/10.1002/ccd.25736
State	Published - Apr 1 2015

Keywords

chronic total occlusions
coronary artery bypass grafting
coronary artery disease
myocardial infarction
percutaneous coronary intervention

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1002/ccd.25736

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Carlino, M., Magri, C. J., Uretsky, B. F., Brilakis, E. S., Walsh, S., Spratt, J. C., Hanratty, C., Grantham, J. A., Rinfret, S., Thompson, C. A., Lombardi, W. L., Galassi, A. R., Sianos, G., Latib, A., Garbo, R., Karmpaliotis, D., Kandzari, D. E., & Colombo, A. (2015). Treatment of the chronic total occlusion: A call to action for the interventional community. Catheterization and Cardiovascular Interventions, 85(5), 771-778. https://doi.org/10.1002/ccd.25736

Carlino, M, Magri, CJ, Uretsky, BF, Brilakis, ES, Walsh, S, Spratt, JC, Hanratty, C, Grantham, JA, Rinfret, S, Thompson, CA, Lombardi, WL, Galassi, AR, Sianos, G, Latib, A, Garbo, R, Karmpaliotis, D, Kandzari, DE & Colombo, A 2015, 'Treatment of the chronic total occlusion: A call to action for the interventional community', Catheterization and Cardiovascular Interventions, vol. 85, no. 5, pp. 771-778. https://doi.org/10.1002/ccd.25736

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abstract = "There is substantial evidence that recanalization of a chronic total occlusion is beneficial; nonetheless, it is generally underutilized in clinical practice. We consider the Aesop's fable of the {"}Fox and the Grapes{"} as analogous to the current situation in interventional cardiology. The technical challenges in achieving CTO recanalization has led interventionalists, clinical cardiologists, and sometimes even patients to believe that CTO recanalization is not effective, and, therefore, not needed. This perspective reviews available data regarding efficacy and safety of CTO percutaneous coronary intervention (PCI) in the current drug-eluting stent era, discusses areas where more studies are required, and encourages the interventional community to utilize CTO PCI where appropriate based on current evidence.",

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author = "Mauro Carlino and Magri, {Caroline J.} and Uretsky, {Barry F.} and Brilakis, {Emmanouil S.} and Simon Walsh and Spratt, {James C.} and Colm Hanratty and Grantham, {J. Aaron} and St{\'e}phane Rinfret and Thompson, {Craig A.} and Lombardi, {William L.} and Galassi, {Alfredo R.} and George Sianos and Azeem Latib and Roberto Garbo and Dimitri Karmpaliotis and Kandzari, {David E.} and Antonio Colombo",

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AU - Walsh, Simon

AU - Spratt, James C.

AU - Hanratty, Colm

AU - Grantham, J. Aaron

AU - Rinfret, Stéphane

AU - Thompson, Craig A.

AU - Lombardi, William L.

AU - Galassi, Alfredo R.

AU - Sianos, George

AU - Latib, Azeem

AU - Garbo, Roberto

AU - Karmpaliotis, Dimitri

AU - Kandzari, David E.

AU - Colombo, Antonio

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KW - chronic total occlusions

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KW - coronary artery disease

KW - myocardial infarction

KW - percutaneous coronary intervention

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Treatment of the chronic total occlusion: A call to action for the interventional community

Abstract

Keywords

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