TY - JOUR
T1 - Treatment of diabetes mellitus
T2 - The future
AU - Raskin, Philip
N1 - Funding Information:
From the Veterans Administration Hospital, Dallas, Tex. and The University of Texas Health Science Center at Dallas, Southwestern MedicalSchool. Department oflnter-nal Medicine, Dallas Tex. Receivefdo r publicalion January 25. 1979. Supported by NIH Grants I-ROI-AMI8179-04 and SMOI-RRO063, the American Diabetes Association, North Texas A@iate. and the American Heart Association. Address reprint requests to Dr. Philip Raskin. The University of Texas Health Science Center at Dallas, Depariment of Inrernal Medicine, 5323 Harry Hines Blvd., Dallas, Tex. 75235. o I979 by Grune & Stratton, Inc. 0026-0495/79/2807~12$02.00/0
PY - 1979/7
Y1 - 1979/7
N2 - For more than half a century the management of hyperglycemia in diabetes mellitus has included rigid diets and intermittent subcutaneous insulin administration. These methods have been totally unsuccessful in restoring glucose homeostasis to normal in most diabetic patients. This review focuses on techniques that offer promise as alternatives or adjuncts to the current modalities of treatment. Specific areas discussed include pancreatic transplantation, islet cell transplantation, artificial beta cell devices, and the glucagon-suppressing agent somatostatin. Although many of these show promise for the future, a cure for the metabolic abnormalities of diabetes is not imminent.
AB - For more than half a century the management of hyperglycemia in diabetes mellitus has included rigid diets and intermittent subcutaneous insulin administration. These methods have been totally unsuccessful in restoring glucose homeostasis to normal in most diabetic patients. This review focuses on techniques that offer promise as alternatives or adjuncts to the current modalities of treatment. Specific areas discussed include pancreatic transplantation, islet cell transplantation, artificial beta cell devices, and the glucagon-suppressing agent somatostatin. Although many of these show promise for the future, a cure for the metabolic abnormalities of diabetes is not imminent.
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U2 - 10.1016/0026-0495(79)90186-0
DO - 10.1016/0026-0495(79)90186-0
M3 - Article
C2 - 109734
AN - SCOPUS:0018761772
SN - 0026-0495
VL - 28
SP - 780
EP - 796
JO - Metabolism: Clinical and Experimental
JF - Metabolism: Clinical and Experimental
IS - 7
ER -