Abstract
Background: Neurological involvement occurs rarely with systemic sclerosis (SSc). Only a few cases of transverse myelopathy have been reported in the setting of SSc. Objective: To describe a patient with SSc who developed transverse myelitis that improved during a course of immunosuppression. Results: A 30-year-old woman with SSc presented with subacute onset of bilateral lower extremity weakness and numbness. Results of magnetic resonance imaging and cerebrospinal fluid studies supported a diagnosis of transverse myelitis. The patient responded favorably to a course of corticosteroids and cyclophosphamide. No overlapping autoimmune disorders were evident. Clinical follow-up showed significant recovery, with resolution of radiological abnormalities. Conclusion: Transverse myelitis can occur as a rare manifestation of SSc and may respond favorably to immunosuppressive therapy.
Original language | English (US) |
---|---|
Pages (from-to) | 126-128 |
Number of pages | 3 |
Journal | Archives of neurology |
Volume | 61 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2004 |
ASJC Scopus subject areas
- Arts and Humanities (miscellaneous)
- Clinical Neurology