Transverse Myelitis in Systemic Sclerosis

Amir M. Torabi, Rahul K. Patel, Gil I. Wolfe, Charlece S. Hughes, Dianne B. Mendelsohn, Jaya R. Trivedi

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Background: Neurological involvement occurs rarely with systemic sclerosis (SSc). Only a few cases of transverse myelopathy have been reported in the setting of SSc. Objective: To describe a patient with SSc who developed transverse myelitis that improved during a course of immunosuppression. Results: A 30-year-old woman with SSc presented with subacute onset of bilateral lower extremity weakness and numbness. Results of magnetic resonance imaging and cerebrospinal fluid studies supported a diagnosis of transverse myelitis. The patient responded favorably to a course of corticosteroids and cyclophosphamide. No overlapping autoimmune disorders were evident. Clinical follow-up showed significant recovery, with resolution of radiological abnormalities. Conclusion: Transverse myelitis can occur as a rare manifestation of SSc and may respond favorably to immunosuppressive therapy.

Original languageEnglish (US)
Pages (from-to)126-128
Number of pages3
JournalArchives of neurology
Issue number1
StatePublished - Jan 2004

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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