Transcription control by long non-coding RNAs

Tyler Faust, Alan D. Frankel, Iván D'Orso

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Non-coding RNAs have been found to regulate many cellular processes and thus expand the functional genetic repertoire contained within the genome. With the recent advent of genomic tools, it is now evident that these RNA molecules play central regulatory roles in many transcriptional programs. Here we discuss how they are targeted to promoters in several cases and how they operate at specific points in the transcription cycle to precisely control gene expression.

Original languageEnglish (US)
Pages (from-to)78-86
Number of pages9
Issue number2
StatePublished - 2012


  • Chromatin
  • Epigenetic silencing
  • Large intergenic non-coding RNAs
  • Long non-coding RNAs
  • RNA polymerase ii
  • Transcription

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Genetics


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