Total skin electron beam radiation in a pediatric patient with leukemia cutis: A case report

Nazanin K. Majd; Sheena K. Jain; Mike C. Murphy; Joseph P. Dugas; Frederick Hager; Ramzi Abdulrahman

doi:10.1097/MPH.0b013e3182678e9f

Total skin electron beam radiation in a pediatric patient with leukemia cutis: A case report

Nazanin K. Majd, Sheena K. Jain, Mike C. Murphy, Joseph P. Dugas, Frederick Hager, Ramzi Abdulrahman

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Leukemia cutis, a form of extramedullary leukemia involving the skin, is a poor prognostic marker and indicator of imminent hematologic relapse and chemotherapeutic resistance in leukemia patients. Although total skin electron beam radiotherapy is commonly recommended for patients with leukemia cutis, its role and effectiveness remains unclear. Here we describe a 19-month-old infant with acute myelogenous leukemia first diagnosed at 15 months of age. It relapsed in her skin at 18 months of age, associated with raised hyperpigmented lesions on her chest and scalp. Radiation treatment to the total skin surface with radiation therapy resulted in relief of her symptoms before relapse in the bone marrow.

Original language	English (US)
Pages (from-to)	556-558
Number of pages	3
Journal	Journal of Pediatric Hematology/Oncology
Volume	34
Issue number	7
DOIs	https://doi.org/10.1097/MPH.0b013e3182678e9f
State	Published - Oct 2012

Keywords

acute myelogenous leukemia
electron beam therapy
extramedullary leukemia
leukemia cutis
total skin irradiation

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

Access to Document

10.1097/MPH.0b013e3182678e9f

Cite this

@article{1bd8816478894be48b944e46afd002c5,

title = "Total skin electron beam radiation in a pediatric patient with leukemia cutis: A case report",

abstract = "Leukemia cutis, a form of extramedullary leukemia involving the skin, is a poor prognostic marker and indicator of imminent hematologic relapse and chemotherapeutic resistance in leukemia patients. Although total skin electron beam radiotherapy is commonly recommended for patients with leukemia cutis, its role and effectiveness remains unclear. Here we describe a 19-month-old infant with acute myelogenous leukemia first diagnosed at 15 months of age. It relapsed in her skin at 18 months of age, associated with raised hyperpigmented lesions on her chest and scalp. Radiation treatment to the total skin surface with radiation therapy resulted in relief of her symptoms before relapse in the bone marrow.",

keywords = "acute myelogenous leukemia, electron beam therapy, extramedullary leukemia, leukemia cutis, total skin irradiation",

author = "Majd, {Nazanin K.} and Jain, {Sheena K.} and Murphy, {Mike C.} and Dugas, {Joseph P.} and Frederick Hager and Ramzi Abdulrahman",

year = "2012",

month = oct,

doi = "10.1097/MPH.0b013e3182678e9f",

language = "English (US)",

volume = "34",

pages = "556--558",

journal = "Journal of Pediatric Hematology/Oncology",

issn = "1077-4114",

publisher = "Lippincott Williams and Wilkins",

number = "7",

}

TY - JOUR

T1 - Total skin electron beam radiation in a pediatric patient with leukemia cutis

T2 - A case report

AU - Majd, Nazanin K.

AU - Jain, Sheena K.

AU - Murphy, Mike C.

AU - Dugas, Joseph P.

AU - Hager, Frederick

AU - Abdulrahman, Ramzi

PY - 2012/10

Y1 - 2012/10

N2 - Leukemia cutis, a form of extramedullary leukemia involving the skin, is a poor prognostic marker and indicator of imminent hematologic relapse and chemotherapeutic resistance in leukemia patients. Although total skin electron beam radiotherapy is commonly recommended for patients with leukemia cutis, its role and effectiveness remains unclear. Here we describe a 19-month-old infant with acute myelogenous leukemia first diagnosed at 15 months of age. It relapsed in her skin at 18 months of age, associated with raised hyperpigmented lesions on her chest and scalp. Radiation treatment to the total skin surface with radiation therapy resulted in relief of her symptoms before relapse in the bone marrow.

AB - Leukemia cutis, a form of extramedullary leukemia involving the skin, is a poor prognostic marker and indicator of imminent hematologic relapse and chemotherapeutic resistance in leukemia patients. Although total skin electron beam radiotherapy is commonly recommended for patients with leukemia cutis, its role and effectiveness remains unclear. Here we describe a 19-month-old infant with acute myelogenous leukemia first diagnosed at 15 months of age. It relapsed in her skin at 18 months of age, associated with raised hyperpigmented lesions on her chest and scalp. Radiation treatment to the total skin surface with radiation therapy resulted in relief of her symptoms before relapse in the bone marrow.

KW - acute myelogenous leukemia

KW - electron beam therapy

KW - extramedullary leukemia

KW - leukemia cutis

KW - total skin irradiation

UR - http://www.scopus.com/inward/record.url?scp=84866895064&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866895064&partnerID=8YFLogxK

U2 - 10.1097/MPH.0b013e3182678e9f

DO - 10.1097/MPH.0b013e3182678e9f

M3 - Article

C2 - 23007342

AN - SCOPUS:84866895064

SN - 1077-4114

VL - 34

SP - 556

EP - 558

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

IS - 7

ER -

Total skin electron beam radiation in a pediatric patient with leukemia cutis: A case report

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this