Toll we meet again

Bruce Beutler; Alexander Poltorak

doi:10.1038/83222

Toll we meet again

Bruce Beutler, Alexander Poltorak

Research output: Contribution to journal › Short survey › peer-review

12 Scopus citations

Abstract

Remodeling of chromatin, distinct from activation of NF-κB, is a newly identified function of Toll-like receptors in mammals. In Drosophila, Toll receptors play a role in development as well as immunity; yet in mammals, they have an immunological role only. Further clues to the evolutionary development of the Toll receptors are emerging.

Original language	English (US)
Pages (from-to)	9-10
Number of pages	2
Journal	Nature Immunology
Volume	2
Issue number	1
DOIs	https://doi.org/10.1038/83222
State	Published - Jan 1 2001

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1038/83222

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abstract = "Remodeling of chromatin, distinct from activation of NF-κB, is a newly identified function of Toll-like receptors in mammals. In Drosophila, Toll receptors play a role in development as well as immunity; yet in mammals, they have an immunological role only. Further clues to the evolutionary development of the Toll receptors are emerging.",

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Toll we meet again

Abstract

ASJC Scopus subject areas

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