Tm(DOTP)5−: A 23Na+ shift agent for perfused rat hearts

D. C. Buster, M. M C A Castro, C. F G C Geraldes, C. R. Malloy, A. D. Sherry, T. C. Siemers

Research output: Contribution to journalArticlepeer-review

120 Scopus citations


Tm(DOTP)5−, the thulium(III) complex of 1,4,7,10‐tetraazacyclododecane N,N′,N″,N‴tetra(methylenephosphonate), is introduced as a 23Na1 shift agent for use in discrimination of the NMR resonances of intra‐ and extracellular 23Na+ ions in perfused rat hearts. The novel shift agent is directly compared to the widely used Dy(TTHA)3‐ (dysprosium(III) triethylenetetraminehexaacetate). © 1990 Academic Press, Inc.

Original languageEnglish (US)
Pages (from-to)25-32
Number of pages8
JournalMagnetic resonance in medicine
Issue number1
StatePublished - Jul 1990

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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