Thiophenyl Derivatives of Nicotinamide Are Metabolized by the NAD Salvage Pathway into Unnatural NAD Derivatives That Inhibit IMPDH and Are Toxic to Peripheral Nerve Cancers

Panayotis C. Theodoropoulos, Holly H. Guo, Wentian Wang, Eric Crossley, Giomar Rivera Cancel, Min Fang, Thu Nguyen, Hamid Baniasadi, Noelle S. Williams, Joseph M. Ready, Jef K. De Brabander, Deepak Nijhawan

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Biochemistry, Genetics and Molecular Biology

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Pharmacology, Toxicology and Pharmaceutical Science