The treatment of systemic lupus proliferative nephritis

Marilynn G. Punaro

doi:10.1007/s00467-012-2327-1

The treatment of systemic lupus proliferative nephritis

Marilynn G. Punaro

Pediatrics

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE) in childhood affecting more than 80 % of patients. Treatment of this complication has undergone significant evolution in recent years. A series of randomized controlled trials has clarified the role of a variety of immunomodulating regimens including some novel biologic medications. This review touches on the major trials that have influenced practice and shaped current thinking about the treatment of proliferative lupus glomerulonephritis.

Original language	English (US)
Pages (from-to)	2069-2078
Number of pages	10
Journal	Pediatric Nephrology
Volume	28
Issue number	11
DOIs	https://doi.org/10.1007/s00467-012-2327-1
State	Published - Nov 1 2013

Keywords

Lupus
Mycophenolate mofetil
Nephritis
Pediatric lupus
Systemic lupus erythematosus

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Nephrology

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10.1007/s00467-012-2327-1

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AB - Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE) in childhood affecting more than 80 % of patients. Treatment of this complication has undergone significant evolution in recent years. A series of randomized controlled trials has clarified the role of a variety of immunomodulating regimens including some novel biologic medications. This review touches on the major trials that have influenced practice and shaped current thinking about the treatment of proliferative lupus glomerulonephritis.

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KW - Mycophenolate mofetil

KW - Nephritis

KW - Pediatric lupus

KW - Systemic lupus erythematosus

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The treatment of systemic lupus proliferative nephritis

Abstract

Keywords

ASJC Scopus subject areas

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