@article{9fc1317bb3a44100b7131845c1d13874,
title = "The synthesis of new, selected analogues of the pro-apoptotic and anticancer molecule HA 14-1",
abstract = "A new and versatile strategy has been developed towards HA 14-1 analogues, selectively modified on position 4 and/or on the primary amine function. An important aspect was the appropriate selection of the phenol protective group in the 5-bromosalicylaldehyde, allowing the isolation of the key intermediate the 2H-benzopyrane-2-imine 2′.",
keywords = "Anticancer, Bcl-2, Benzopyrane, HA 14-1",
author = "Danielle Gr{\'e}e and Samuel Vorin and Manthati, {Vijay L.} and Fr{\'e}d{\'e}ric Caijo and Guillaume Viault and Florence Manero and Philippe Juin and Ren{\'e} Gr{\'e}e",
note = "Funding Information: We thank Laboratoires Servier for support of this research and we thank Drs. O. Geneste, B. Pfeiffer, L. Oliver and F. Vallette for fruitful discussions. We thank the Ligue contre le Cancer (Comit{\'e} d{\textquoteright}Ille et Vilaine) for fellowships to V.L.M and G.V. Furthermore, P.J. is supported by R{\'e}gion Pays de la Loire (CIMATH network), ARC (Ref. 3875) and Institut de Recherche Servier.",
year = "2008",
month = may,
day = "12",
doi = "10.1016/j.tetlet.2008.03.070",
language = "English (US)",
volume = "49",
pages = "3276--3278",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "20",
}