The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations

Rod J. Rohrich, Min Jeong Cho

Research output: Contribution to journalReview articlepeer-review

56 Scopus citations


Minimizing blood loss during surgery is critical, and many modalities have been used to decrease unwanted surgical bleeding. Among many methods, use of pharmacologic agents such as antifibrinolytic drugs has been shown to significantly reduce blood loss and the rates of postoperative blood transfusion in many articles. Tranexamic acid is an antifibrinolytic agent that has been widely used in other surgical specialties, especially in cardiac, orthopedic, and trauma surgery. Despite its known benefits, the use of tranexamic acid in plastic surgery is extremely limited, primarily because most plastic surgery procedures do not involve the extent of blood loss that can lead to anemia and the need for blood transfusion, as is common in major orthopedic and cardiac surgery procedures. Nevertheless, there are significant benefits to be gained from the use of antifibrinolytic drugs in the full range of plastic surgery. In this article, the authors introduce the benefits, dosages, and technical considerations of using tranexamic acid in plastic surgery procedures.

Original languageEnglish (US)
Pages (from-to)507-515
Number of pages9
JournalPlastic and Reconstructive Surgery
Issue number2
StatePublished - Feb 1 2018

ASJC Scopus subject areas

  • Surgery


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