The obstetric and neonatal implications of a low value on the 50-g glucose screening test

Kimberly K. Ma; Lisa Mele; Mark B. Landon; Catherine Y. Spong; Susan M. Ramin; Brian Casey; Ronald J. Wapner; Michael W. Varner; Dwight J. Rouse; John M. Thorp; Anthony Sciscione; Patrick Catalano; Margaret Harper; George Saade; Steve N. Caritis; Yoram Sorokin; Alan M. Peaceman

doi:10.1055/s-0032-1331027

The obstetric and neonatal implications of a low value on the 50-g glucose screening test

Kimberly K. Ma, Lisa Mele, Mark B. Landon, Catherine Y. Spong, Susan M. Ramin, Brian Casey, Ronald J. Wapner, Michael W. Varner, Dwight J. Rouse, John M. Thorp, Anthony Sciscione, Patrick Catalano, Margaret Harper, George Saade, Steve N. Caritis, Yoram Sorokin, Alan M. Peaceman

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Objective To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes. Study Design This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL. Results Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results. Conclusion A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.

Original language	English (US)
Pages (from-to)	715-721
Number of pages	7
Journal	American Journal of Perinatology
Volume	30
Issue number	9
DOIs	https://doi.org/10.1055/s-0032-1331027
State	Published - 2013

Keywords

low glucose screening test
neonatal hypoglycemia

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1055/s-0032-1331027

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Ma, K. K., Mele, L., Landon, M. B., Spong, C. Y., Ramin, S. M., Casey, B., Wapner, R. J., Varner, M. W., Rouse, D. J., Thorp, J. M., Sciscione, A., Catalano, P., Harper, M., Saade, G., Caritis, S. N., Sorokin, Y., & Peaceman, A. M. (2013). The obstetric and neonatal implications of a low value on the 50-g glucose screening test. American Journal of Perinatology, 30(9), 715-721. https://doi.org/10.1055/s-0032-1331027

Ma, KK, Mele, L, Landon, MB, Spong, CY, Ramin, SM, Casey, B, Wapner, RJ, Varner, MW, Rouse, DJ, Thorp, JM, Sciscione, A, Catalano, P, Harper, M, Saade, G, Caritis, SN, Sorokin, Y & Peaceman, AM 2013, 'The obstetric and neonatal implications of a low value on the 50-g glucose screening test', American Journal of Perinatology, vol. 30, no. 9, pp. 715-721. https://doi.org/10.1055/s-0032-1331027

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title = "The obstetric and neonatal implications of a low value on the 50-g glucose screening test",

abstract = "Objective To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes. Study Design This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL. Results Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results. Conclusion A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.",

keywords = "low glucose screening test, neonatal hypoglycemia",

author = "Ma, {Kimberly K.} and Lisa Mele and Landon, {Mark B.} and Spong, {Catherine Y.} and Ramin, {Susan M.} and Brian Casey and Wapner, {Ronald J.} and Varner, {Michael W.} and Rouse, {Dwight J.} and Thorp, {John M.} and Anthony Sciscione and Patrick Catalano and Margaret Harper and George Saade and Caritis, {Steve N.} and Yoram Sorokin and Peaceman, {Alan M.}",

year = "2013",

doi = "10.1055/s-0032-1331027",

language = "English (US)",

volume = "30",

pages = "715--721",

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T1 - The obstetric and neonatal implications of a low value on the 50-g glucose screening test

AU - Ma, Kimberly K.

AU - Mele, Lisa

AU - Landon, Mark B.

AU - Spong, Catherine Y.

AU - Ramin, Susan M.

AU - Casey, Brian

AU - Wapner, Ronald J.

AU - Varner, Michael W.

AU - Rouse, Dwight J.

AU - Thorp, John M.

AU - Sciscione, Anthony

AU - Catalano, Patrick

AU - Harper, Margaret

AU - Saade, George

AU - Caritis, Steve N.

AU - Sorokin, Yoram

AU - Peaceman, Alan M.

PY - 2013

Y1 - 2013

N2 - Objective To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes. Study Design This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL. Results Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results. Conclusion A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.

AB - Objective To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes. Study Design This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL. Results Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results. Conclusion A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.

KW - low glucose screening test

KW - neonatal hypoglycemia

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The obstetric and neonatal implications of a low value on the 50-g glucose screening test

Abstract

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