The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress

Rilee D. Zeinert; Hamid Baniasadi; Benjamin P. Tu; Peter Chien

doi:10.1016/j.molcel.2020.07.011

The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress

Rilee D. Zeinert, Hamid Baniasadi, Benjamin P. Tu, Peter Chien

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Competition between misfolded and natively folded substrates for a limited pool of the highly conserved Lon protease governs stress adaptation.

Original language	English (US)
Pages (from-to)	758-767.e6
Journal	Molecular cell
Volume	79
Issue number	5
DOIs	https://doi.org/10.1016/j.molcel.2020.07.011
State	Published - Sep 3 2020

Keywords

AAA+ protease
chaperone titration
proteotoxic stress
quality control
transposon sequencing

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2020.07.011

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title = "The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress",

abstract = "Competition between misfolded and natively folded substrates for a limited pool of the highly conserved Lon protease governs stress adaptation.",

keywords = "AAA+ protease, chaperone titration, proteotoxic stress, quality control, transposon sequencing",

author = "Zeinert, {Rilee D.} and Hamid Baniasadi and Tu, {Benjamin P.} and Peter Chien",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = sep,

day = "3",

doi = "10.1016/j.molcel.2020.07.011",

language = "English (US)",

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T1 - The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress

AU - Zeinert, Rilee D.

AU - Baniasadi, Hamid

AU - Tu, Benjamin P.

AU - Chien, Peter

PY - 2020/9/3

Y1 - 2020/9/3

N2 - Competition between misfolded and natively folded substrates for a limited pool of the highly conserved Lon protease governs stress adaptation.

AB - Competition between misfolded and natively folded substrates for a limited pool of the highly conserved Lon protease governs stress adaptation.

KW - AAA+ protease

KW - chaperone titration

KW - proteotoxic stress

KW - quality control

KW - transposon sequencing

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M3 - Article

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SN - 1097-2765

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SP - 758-767.e6

JO - Molecular cell

JF - Molecular cell

IS - 5

ER -

The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress

Abstract

Keywords

ASJC Scopus subject areas

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