@article{c84e762e10224057be932af010383d38,
title = "The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress",
abstract = "Competition between misfolded and natively folded substrates for a limited pool of the highly conserved Lon protease governs stress adaptation.",
keywords = "AAA+ protease, chaperone titration, proteotoxic stress, quality control, transposon sequencing",
author = "Zeinert, {Rilee D.} and Hamid Baniasadi and Tu, {Benjamin P.} and Peter Chien",
note = "Funding Information: We thank the Chien, Strieter, Stratton, Serio, and Tu lab members for helpful comments and discussion on the manuscript. We thank Lucy Shapiro for providing CcrM antibody. This project was supported by funds from the National Institutes of Health (NIH) (R35GM130320 to P.C. and R01GM094314 to B.P.T.). R.D.Z. was supported in part through the UMass NIH Chemistry Biology Interface Training Program (NIH T32GM008515). We thank the Genomics Resource Laboratory (Institute for Applied Life Sciences; University of Massachusetts Amherst) for genomics services and equipment support. Conceptualization, R.D.Z. and P.C.; Investigation, R.D.Z. and H.B.; Writing, R.D.Z. and P.C.; Funding Acquisition, P.C. and B.P.T.; Supervision, P.C. and B.P.T. The authors declare no competing interests. Funding Information: We thank the Chien, Strieter, Stratton, Serio, and Tu lab members for helpful comments and discussion on the manuscript. We thank Lucy Shapiro for providing CcrM antibody. This project was supported by funds from the National Institutes of Health ( NIH ) ( R35GM130320 to P.C. and R01GM094314 to B.P.T.). R.D.Z. was supported in part through the UMass NIH Chemistry Biology Interface Training Program ( NIH T32GM008515 ). We thank the Genomics Resource Laboratory ( Institute for Applied Life Sciences ; University of Massachusetts Amherst ) for genomics services and equipment support. Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = sep,
day = "3",
doi = "10.1016/j.molcel.2020.07.011",
language = "English (US)",
volume = "79",
pages = "758--767.e6",
journal = "Molecular cell",
issn = "1097-2765",
publisher = "Cell Press",
number = "5",
}