The life cycle of lipid droplets

Hayaa F. Hashemi, Joel M. Goodman

Research output: Contribution to journalReview articlepeer-review

125 Scopus citations


Proteomic studies have revealed many potential functions of cytoplasmic lipid droplets, and recent activity has confirmed that these bona fide organelles are central not only for lipid storage and metabolism, but for development, immunity, and pathogenesis by several microbes. There has been a burst of recent activity on the assembly, maintenance and turnover of lipid droplets that reveals fresh insights. This review summarizes several novel findings in initiation of lipid droplet assembly, protein targeting, droplet fusion, and turnover of droplets through lipophagy.

Original languageEnglish (US)
Pages (from-to)119-124
Number of pages6
JournalCurrent Opinion in Cell Biology
StatePublished - Apr 1 2015

ASJC Scopus subject areas

  • Cell Biology


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