The interpretation and diagnostic value of oximetrically-recorded T-1824 dye curves in congenital heart disease

Carleton B. Chapman, Jere H. Mitchell, Jack F. Glover, William F. Miller

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Oximetrically recorded T-1824 dye curves offer a relatively reliable means of identifying the site and type of intracardiac and aortic-pulmonary shunts. The most valid indication of the presence of venoarterial admixture is a shortened appearance time (AT). Curves due to left-to-right shunts can be identified by the presence of a normal appearance time and a prolonged descending slope to which disappearance time (DT) is a good index. The use of ratios between certain time intervals obtained from the curves is of questionable value for the identification of the type of shunt present. Double-peaked dye curves usually, but not always, indicate venoarterial admixture but are not as frequently encountered in patients with such shunts as are shortened appearance times. Comparison of oximetric dye curves and those obtained by serial arterial sampling in normal subjects discloses that the former are quantitatively reliable both as to time intervals and as to the area enclosed, provided 10 mg. or more of dye is injected.

Original languageEnglish (US)
Pages (from-to)519-529
Number of pages11
JournalAmerican heart journal
Volume53
Issue number4
DOIs
StatePublished - Apr 1957

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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