TY - JOUR
T1 - The Interconnections of Mal de Débarquement Syndrome and Vestibular Migraine
AU - Beh, Shin C.
AU - Chiang, Hsueh Sheng
AU - Sanderson, Collin
N1 - Publisher Copyright:
© 2020 American Laryngological, Rhinological and Otological Society Inc, "The Triological Society" and American Laryngological Association (ALA)
PY - 2021/5
Y1 - 2021/5
N2 - Objectives/Hypothesis: Mal de débarquement syndrome (MDDS) is characterized by a persistent rocking sensation, as though on a boat. It may occur following exposure to passive motion (motion-triggered MDDS [MT-MDDS]), or spontaneously (spontaneous-onset MDDS [SO-MDDS]). This study investigated the characteristics of MDDS patients with vestibular migraine (MDDS-VM) to those without (MDDS-O). Study Design: Retrospective review. Methods: Retrospective, single-center study of 62 patients with MDDS. Clinical characteristics, Dizziness Handicap Inventory (DHI), Migraine Disability Assessment Score (MIDAS), job impact, and optimal treatment(s) were studied. Results: There were 23 MDDS-O (19 women), and 39 MDDS-VM (35 women) patients. Comparisons between MDDS-VM and MDDS-O showed significant differences in age of onset (41 vs. 52 years, P =.005), interictal visually induced dizziness (89.7% vs. 30.4%, P <.001), interictal head motion-induced dizziness (87.2% vs. 47.8%, P =.001), other vestibular sensations (59% vs. 13%, P <.001), interictal aural symptoms (25.6% vs. 0%, P =.008), number of interictal symptoms (4.3 vs. 2.3, P <.001), total DHI score (54.9 vs. 38.1, P =.005), DHI-P (physical domain) score (16.1 vs. 10, P =.004), DHI-F (functional domain) score (20.9 vs. 15.7, P =.016 MIDAS (4.6 vs. 32, P =.002), and job resignations (23.2% vs. 5%, P =.016). On the other hand, between-group comparisons for MT-MDDS and SO-MDDS did not reveal any significant differences whatsoever. For optimal treatment, venlafaxine was the most used (27.3%) in all groups. For MDDS-VM, antiepileptic drugs and migraine preventive vitamins were also useful in relieving symptoms. Conclusions: MDDS-VM patients appear to be more disabled than MDDS-O, in terms of severity of dizziness, job impact, and number of symptoms, but have good potential for improvement, particularly with migraine prophylactic treatment. Level of Evidence: 3 Laryngoscope, 131:E1653–E1661, 2021.
AB - Objectives/Hypothesis: Mal de débarquement syndrome (MDDS) is characterized by a persistent rocking sensation, as though on a boat. It may occur following exposure to passive motion (motion-triggered MDDS [MT-MDDS]), or spontaneously (spontaneous-onset MDDS [SO-MDDS]). This study investigated the characteristics of MDDS patients with vestibular migraine (MDDS-VM) to those without (MDDS-O). Study Design: Retrospective review. Methods: Retrospective, single-center study of 62 patients with MDDS. Clinical characteristics, Dizziness Handicap Inventory (DHI), Migraine Disability Assessment Score (MIDAS), job impact, and optimal treatment(s) were studied. Results: There were 23 MDDS-O (19 women), and 39 MDDS-VM (35 women) patients. Comparisons between MDDS-VM and MDDS-O showed significant differences in age of onset (41 vs. 52 years, P =.005), interictal visually induced dizziness (89.7% vs. 30.4%, P <.001), interictal head motion-induced dizziness (87.2% vs. 47.8%, P =.001), other vestibular sensations (59% vs. 13%, P <.001), interictal aural symptoms (25.6% vs. 0%, P =.008), number of interictal symptoms (4.3 vs. 2.3, P <.001), total DHI score (54.9 vs. 38.1, P =.005), DHI-P (physical domain) score (16.1 vs. 10, P =.004), DHI-F (functional domain) score (20.9 vs. 15.7, P =.016 MIDAS (4.6 vs. 32, P =.002), and job resignations (23.2% vs. 5%, P =.016). On the other hand, between-group comparisons for MT-MDDS and SO-MDDS did not reveal any significant differences whatsoever. For optimal treatment, venlafaxine was the most used (27.3%) in all groups. For MDDS-VM, antiepileptic drugs and migraine preventive vitamins were also useful in relieving symptoms. Conclusions: MDDS-VM patients appear to be more disabled than MDDS-O, in terms of severity of dizziness, job impact, and number of symptoms, but have good potential for improvement, particularly with migraine prophylactic treatment. Level of Evidence: 3 Laryngoscope, 131:E1653–E1661, 2021.
KW - dizziness
KW - mal de débarquement syndrome
KW - migraine
KW - vertigo
KW - vestibular migraine
UR - http://www.scopus.com/inward/record.url?scp=85096882030&partnerID=8YFLogxK
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U2 - 10.1002/lary.29214
DO - 10.1002/lary.29214
M3 - Article
C2 - 33135784
AN - SCOPUS:85096882030
SN - 0023-852X
VL - 131
SP - E1653-E1661
JO - Laryngoscope
JF - Laryngoscope
IS - 5
ER -