TY - JOUR
T1 - The influence of age on the response of major depression to electroconvulsive therapy
T2 - A C.O.R.E. report
AU - O'Connor, M. Kevin
AU - Knapp, Rebecca
AU - Husain, Mustafa
AU - Rummans, Teresa A.
AU - Petrides, Georgios
AU - Smith, Glenn
AU - Mueller, Martina
AU - Snyder, Karen
AU - Bernstein, Hilary
AU - Rush, A. John
AU - Fink, Max
AU - Kellner, Charles
PY - 2001
Y1 - 2001
N2 - As part of a C.O.R.E., multi-site longitudinal study comparing continuation electro-convulsive therapy (ECT) vs. continuation pharmacotherapy, the authors determined the response of 253 patients with major depression to acute-phase, bilateral ECT by use of the 24-item Hamilton Rating Scale for Depression. Remission rates for three age-groups, ≥65 years; 46-64 years; and ≤45 years, were 90 percent, 89.8 percent, and 70 percent, respectively. Age, as a continuous variable, positively influenced response to treatment. Bilateral, dose-titrated ECT is a highly effective acute treatment for major depression, and older age confers a greater likelihood of achieving remission.
AB - As part of a C.O.R.E., multi-site longitudinal study comparing continuation electro-convulsive therapy (ECT) vs. continuation pharmacotherapy, the authors determined the response of 253 patients with major depression to acute-phase, bilateral ECT by use of the 24-item Hamilton Rating Scale for Depression. Remission rates for three age-groups, ≥65 years; 46-64 years; and ≤45 years, were 90 percent, 89.8 percent, and 70 percent, respectively. Age, as a continuous variable, positively influenced response to treatment. Bilateral, dose-titrated ECT is a highly effective acute treatment for major depression, and older age confers a greater likelihood of achieving remission.
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U2 - 10.1097/00019442-200111000-00006
DO - 10.1097/00019442-200111000-00006
M3 - Article
C2 - 11739064
AN - SCOPUS:0034749933
SN - 1064-7481
VL - 9
SP - 382
EP - 390
JO - American Journal of Geriatric Psychiatry
JF - American Journal of Geriatric Psychiatry
IS - 4
ER -