The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis

Russ Riddle; Christina N. Ryser; Anne A. Morton; J. D. Sampson; Richard H. Browne; Marilynn G. Punaro; Robert J. Gatchel

doi:10.1093/jpepsy/jsj014

The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis

Russ Riddle, Christina N. Ryser, Anne A. Morton, J. D. Sampson, Richard H. Browne, Marilynn G. Punaro, Robert J. Gatchel

Pediatrics

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Objective: To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). Methods: Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. Results: Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. Conclusion: These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects.

Original language	English (US)
Pages (from-to)	262-271
Number of pages	10
Journal	Journal of pediatric psychology
Volume	31
Issue number	3
DOIs	https://doi.org/10.1093/jpepsy/jsj014
State	Published - Apr 2006

Keywords

Health-related quality of life
Juvenile arthritis
Outcomes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental and Educational Psychology

Access to Document

10.1093/jpepsy/jsj014

Cite this

@article{2f3a7067ff3d44b4939c0ff04a1d1399,

title = "The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis",

abstract = "Objective: To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). Methods: Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. Results: Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. Conclusion: These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects.",

keywords = "Health-related quality of life, Juvenile arthritis, Outcomes",

author = "Russ Riddle and Ryser, {Christina N.} and Morton, {Anne A.} and Sampson, {J. D.} and Browne, {Richard H.} and Punaro, {Marilynn G.} and Gatchel, {Robert J.}",

year = "2006",

month = apr,

doi = "10.1093/jpepsy/jsj014",

language = "English (US)",

volume = "31",

pages = "262--271",

journal = "Journal of pediatric psychology",

issn = "0146-8693",

publisher = "Oxford University Press",

number = "3",

}

TY - JOUR

T1 - The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis

AU - Riddle, Russ

AU - Ryser, Christina N.

AU - Morton, Anne A.

AU - Sampson, J. D.

AU - Browne, Richard H.

AU - Punaro, Marilynn G.

AU - Gatchel, Robert J.

PY - 2006/4

Y1 - 2006/4

N2 - Objective: To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). Methods: Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. Results: Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. Conclusion: These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects.

AB - Objective: To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). Methods: Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. Results: Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. Conclusion: These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects.

KW - Health-related quality of life

KW - Juvenile arthritis

KW - Outcomes

UR - http://www.scopus.com/inward/record.url?scp=33644924918&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33644924918&partnerID=8YFLogxK

U2 - 10.1093/jpepsy/jsj014

DO - 10.1093/jpepsy/jsj014

M3 - Article

C2 - 15872147

AN - SCOPUS:33644924918

SN - 0146-8693

VL - 31

SP - 262

EP - 271

JO - Journal of pediatric psychology

JF - Journal of pediatric psychology

IS - 3

ER -

The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this