The impact of extreme-risk cases on hospitals' risk-adjusted percutaneous coronary intervention mortality ratings

Matthew W. Sherwood, J. Matthew Brennan, Kalon K. Ho, Frederick A. Masoudi, John C. Messenger, W. Douglas Weaver, David Dai, Eric D. Peterson

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


OBJECTIVES: The goal of this study was to examine the calibration of a validated risk-adjustment model in very high-risk percutaneous coronary intervention (PCI) cases and assess whether sites' case mix affects their performance ratings. BACKGROUND: There are concerns that treating PCI patients with particularly high-risk features such as cardiogenic shock or prior cardiac arrest may adversely impact hospital performance ratings. However, there is little investigation on the validity of these concerns. METHODS: We examined 624,286 PCI procedures from 1,168 sites that participated in the CathPCI Registry in 2010. Procedural risk was estimated using the recently published Version 4 National Cardiovascular Data Registry (NCDR) PCI risk-adjusted mortality (RAM) model. We calculated observed/expected mortality using several risk classification methods, and simulated hospital performance after combining their highest risk cases over 2 years into a single year. RESULTS: In 2010, crude in-hospital PCI mortality was 1.4%. The NCDR model was generally well calibrated among high risk, however there was slight overprediction of risk in extreme cases. Hospitals treating the highest overall expected risk PCI patients or those treating the top 20% of high-risk cases had lower (better) RAM ratings than centers treating lower-risk cases (1.25% vs. 1.51%). The observed/expected ratio for top-risk quintile versus low-risk quintile was 0.91 (0.87 to 0.96) versus 1.10 (1.03 to 1.17). Combining all the high-risk patients over a 2-year period into a single year also did not negatively impact the site's RAM ratings. CONCLUSIONS: Evaluation of a contemporary sample of PCI cases across the United States showed no evidence that treating high-risk PCI cases adversely affects hospital RAM rates.

Original languageEnglish (US)
Pages (from-to)10-16
Number of pages7
JournalJACC: Cardiovascular Interventions
Issue number1
StatePublished - Jan 1 2015
Externally publishedYes


  • Intervention
  • Percutaneous coronary
  • Risk-adjusted mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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