The eye and headache

Deborah I. Friedman

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Purpose of Review: This article highlights painful conditions involving the eyes that are encountered in practice, emphasizing those that do not have obvious findings on the neurologic examination. Recent Findings: Peripheral and central sensitization are associated with chronic neuropathic ocular pain, and hyperalgesia is associated with dry eyes. The aorta and its branches are involved in 25% of patients with giant cell arteritis. Summary: Eye pain is a common concern and one of the most difficult symptoms for the clinician to evaluate. Eye pain may be a manifestation of a primary headache disorder, as is common in migraine, the trigeminal autonomic cephalalgias, and primary stabbing headache. Secondary headache disorders, such as posterior communicating artery aneurysm, Tolosa-Hunt syndrome, and microvascular ocular motor neuropathies, frequently produce eye pain. Ophthalmic conditions producing eye pain include orbital masses, angle-closure glaucoma, intraocular inflammation, and ocular surface (corneal) disease. Of these, corneal problems are themost commonly encountered.

Original languageEnglish (US)
Pages (from-to)1109-1117
Number of pages9
JournalCONTINUUM Lifelong Learning in Neurology
Issue number4
StatePublished - Aug 2015

ASJC Scopus subject areas

  • Clinical Neurology
  • Genetics(clinical)


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