The expression pattern of endothelin 3 in the avian embryo

V. Nataf, A. Amemiya, Masashi Yanagisawa, N. M. Le Douarin

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


We investigated the expression pattern of the endothelin 3 gene, of which the mutation, as well as mutation of its receptor (endothelin-B receptor), affects the development of two neural crest derivatives: enteric nervous system and melanocytes. After previous work showing that these neural crest derived cells express endothelin-B receptor or its subtype endothelin- B2 receptor in the avian embryo, we have demonstrated that endothelin 3 is expressed by the environment of enteric nervous system and melanocyte precursors.

Original languageEnglish (US)
Pages (from-to)217-220
Number of pages4
JournalMechanisms of Development
Issue number2
StatePublished - May 1998


  • Avian
  • Embryo
  • Endothelin 3
  • Enteric nervous system
  • Expression pattern
  • Melanocytes

ASJC Scopus subject areas

  • Embryology
  • Developmental Biology


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