Abstract
We investigated the expression pattern of the endothelin 3 gene, of which the mutation, as well as mutation of its receptor (endothelin-B receptor), affects the development of two neural crest derivatives: enteric nervous system and melanocytes. After previous work showing that these neural crest derived cells express endothelin-B receptor or its subtype endothelin- B2 receptor in the avian embryo, we have demonstrated that endothelin 3 is expressed by the environment of enteric nervous system and melanocyte precursors.
Original language | English (US) |
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Pages (from-to) | 217-220 |
Number of pages | 4 |
Journal | Mechanisms of Development |
Volume | 73 |
Issue number | 2 |
DOIs | |
State | Published - May 1998 |
Keywords
- Avian
- Embryo
- Endothelin 3
- Enteric nervous system
- Expression pattern
- Melanocytes
ASJC Scopus subject areas
- Embryology
- Developmental Biology