The cyclin-dependent kinase 2 inhibitor down-regulates interleukin-1β- mediated induction of cyclooxygenase-2 expression in human lung carcinoma cells

Medicine & Life Sciences

• Cyclin-Dependent Kinase 2 100%
• Cyclooxygenase 2 73%
• N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-piperidinecarboxamide 70%
• Interleukin-1 70%
• Down-Regulation 49%
• Carcinoma 46%
• Lung 37%
• Phosphotransferases 13%
• CCAAT-Enhancer-Binding Protein-beta 12%
• Cell Cycle Proteins 10%
• Cyclin-Dependent Kinases 10%
• Mitogen-Activated Protein Kinase 3 10%
• Mitogen-Activated Protein Kinase 1 9%
• Heat-Shock Proteins 9%
• p38 Mitogen-Activated Protein Kinases 9%
• S Phase 8%
• Prostaglandins 8%
• Protein Kinases 8%
• Non-Small Cell Lung Carcinoma 7%
• Small Interfering RNA 7%
• Colon 7%
• Lung Neoplasms 6%
• Cell Cycle 6%
• Neck 6%
• Head 6%
• Cell Line 5%
• Messenger RNA 5%
• In Vitro Techniques 3%
• Genes 3%
• Neoplasms 2%