The current use of stem cells in bladder tissue regeneration and bioengineering

Yvonne Y. Chan, Samantha K. Sandlin, Eric A. Kurzrock, Stephanie L. Osborn

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations

Abstract

Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder stones, and other long-term sequelae, raising the need for a source of safe and reliable bladder tissue. Advancements in stem cell biology have catapulted stem cells to the center of many current tissue regeneration and bioengineering strategies. This review presents the recent advancements in the use of stem cells in bladder tissue bioengineering.

Original languageEnglish (US)
Article number4
JournalBiomedicines
Volume5
Issue number1
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

Keywords

  • Bladder
  • Stem cells
  • Tissue engineering
  • Urothelium

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)

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