The active role of βγ in signal transduction

Research output: Contribution to journalArticlepeer-review

102 Scopus citations


Many receptors that sense the environment effect intracellular regulation through stimulation of heterotrimeric G proteins and the consequences thereof. While prominence was originally given to the α-subunits of G proteins as the pathway for downstream regulation, very active roles for the βγ-subunits have emerged in the past year. Recent experiments highlight the versatility of βγ-subunits in these regulatory pathways, but also emphasize some fundamental questions that remain.

Original languageEnglish (US)
Pages (from-to)198-203
Number of pages6
JournalCurrent Opinion in Cell Biology
Issue number2
StatePublished - Apr 1994

ASJC Scopus subject areas

  • Cell Biology


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