TY - JOUR
T1 - The activated keratinocyte
T2 - Up regulation of cell adhesion and migration during wound healing
AU - Grinnell, F.
PY - 1990/12
Y1 - 1990/12
N2 - Keratinocytes play different roles in normal and wounded skin. In normal skin, these cells are specialized for differentiation. In wounded skin, they are specialized for migration. This article discusses the idea that migratory-competent keratinocytes are “activated.” Changes that characterize the activation process include increased cell attachment, spreading, focal adhesion formation, and migration. In part, these changes can be explained by enhanced expression of α5 integrin subunits and reorganization of β1 integrin subunits.
AB - Keratinocytes play different roles in normal and wounded skin. In normal skin, these cells are specialized for differentiation. In wounded skin, they are specialized for migration. This article discusses the idea that migratory-competent keratinocytes are “activated.” Changes that characterize the activation process include increased cell attachment, spreading, focal adhesion formation, and migration. In part, these changes can be explained by enhanced expression of α5 integrin subunits and reorganization of β1 integrin subunits.
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M3 - Article
C2 - 2254973
AN - SCOPUS:0025638885
SN - 0022-5282
VL - 30
SP - S144-S149
JO - Journal of Trauma - Injury, Infection and Critical Care
JF - Journal of Trauma - Injury, Infection and Critical Care
IS - 12
ER -