The 2014 San Antonio breast cancer symposium: A successful lift-off for breast immunotherapy?

David B. Page; Jarushka Naidoo; Heather L. McArthur

doi:10.1038/npjbcancer.2015.1

The 2014 San Antonio breast cancer symposium: A successful lift-off for breast immunotherapy?

David B. Page, Jarushka Naidoo, Heather L. McArthur

Research output: Contribution to journal › Article › peer-review

Abstract

Therapeutic immune checkpoint antibodies promote potentially durable cancer control by modulating key regulatory factors of the endogenous anti-tumor immune response. The first clinical trial data of these agents in breast cancer were presented at the 2014 San Antonio Breast Cancer Symposium, with seemingly modest response rates compared with metastatic melanoma and Hodgkin’s lymphoma. In this article, we review the San Antonio immunotherapy data, drawing key analogies to historical experiences in metastatic melanoma that support an enthusiastic outlook for immunotherapy in breast cancer.

Original language	English (US)
Article number	15001
Journal	npj Breast Cancer
Volume	1
DOIs	https://doi.org/10.1038/npjbcancer.2015.1
State	Published - 2015
Externally published	Yes

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Pharmacology (medical)

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10.1038/npjbcancer.2015.1

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title = "The 2014 San Antonio breast cancer symposium: A successful lift-off for breast immunotherapy?",

abstract = "Therapeutic immune checkpoint antibodies promote potentially durable cancer control by modulating key regulatory factors of the endogenous anti-tumor immune response. The first clinical trial data of these agents in breast cancer were presented at the 2014 San Antonio Breast Cancer Symposium, with seemingly modest response rates compared with metastatic melanoma and Hodgkin{\textquoteright}s lymphoma. In this article, we review the San Antonio immunotherapy data, drawing key analogies to historical experiences in metastatic melanoma that support an enthusiastic outlook for immunotherapy in breast cancer.",

author = "Page, {David B.} and Jarushka Naidoo and McArthur, {Heather L.}",

note = "Publisher Copyright: {\textcopyright} 2015 Breast Cancer Research Foundation/Macmillan Publishers Limited.",

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The 2014 San Antonio breast cancer symposium: A successful lift-off for breast immunotherapy?

Abstract

ASJC Scopus subject areas

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